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scispaCy — Biomedical & Scientific NLP Models

Allen AI's Apache-2.0 spaCy models for biomedical text with UMLS, MeSH, GO, HPO, and RxNorm entity linking and NER for genes, diseases, chemicals, and proteins.

@ai-supply
Installs98k
⟳ upstream v0.6.2 · updated 9mo ago
↗ Source repository
← More HealthcareHealthcare leaderboard →How we grade security →Source ↗
✓ Grade A · 100/100 · SafeSecurity assessment
✓No compromise signals9capabilities surfaced11of 20 OWASP controls clear
External endpoints declaredExternal endpoints declaredExternal endpoints declaredExternal endpoints declared
scanned 16d ago·osv · gitleaks · opengrep · picklescan + heuristics·full breakdown in the Security tab ↓

scispaCy — Biomedical & Scientific NLP Models

scispaCy by AllenAI provides spaCy-compatible NLP models and pipelines specifically trained on biomedical and scientific text (PubMed, MIMIC-III, BC5CDR, JNLPBA). It includes entity linkers for major biomedical ontologies — UMLS, MeSH, Gene Ontology, Human Phenotype Ontology, and RxNorm.

Key Features

  • 5 pre-trained spaCy models (sm/md/lg/transformer variants) for biomedical NER
  • Entity types: disease, chemical, gene, protein, cell line, DNA, RNA, cell type
  • Entity linkers: UMLS (3M+ concepts), MeSH, GO, HPO, RxNorm
  • Abbreviation detection (biomedical abbreviations expand correctly)
  • Fully compatible with the spaCy ecosystem (stanza, transformers pipeline)

Quick Start

pip install scispacy
pip install https://s3-us-west-2.amazonaws.com/ai2-s2-scispacy/releases/v0.5.4/en_core_sci_lg-0.5.4.tar.gz
import spacy, scispacy
from scispacy.linking import EntityLinker

nlp = spacy.load("en_core_sci_lg")
nlp.add_pipe("scispacy_linker", config={"resolve_abbreviations": True, "linker_name": "umls"})
doc = nlp("Metformin is used to treat type 2 diabetes mellitus.")
for ent in doc.ents:
    print(ent.text, ent._.kb_ents[:2])
npx ai-supply add scispacy-biomedical-nlp

Curated mirror of the open-source scispaCy (Apache-2.0). Get it from the source.

Rating rank
#1
of 11 in Healthcare
Install rank
#2
of 11 in Healthcare
Security score
100/100 · A
safe
Security rank
#1
of 11 in Healthcare
Installs
98k
cat avg 63k
This listing vs category average
Installs
this
cat avg
Security (of 100)
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✓ Security: Safe · 100100/100 · grade Ascanned 16d ago
✓ no compromise signals9 risk-surface · 4/20 OWASP controls flagged

Compromise signals — malicious or tampered code (leaked secrets, backdoors, a dropped executable) — reduce the score, and known dependency CVEs carry a bounded penalty (they warrant review but never QUARANTINE — update the dependency to clear). Other dangerous-by-capability traits are risk surface, expected for some capabilities. Every finding is mapped to its OWASP control below.

What this capability can do · med confidence (static)
⚑ filesystem⚑ shell⚑ network⚑ secrets
egress → help.github.com, s3-us-west-2.amazonaws.com, scispacy.apps.allenai.org, mamba.readthedocs.io, spacy.io, www.nlm.nih.gov, geneontology.org, hpo.jax.org +19
30 scripts

Findings mapped to the OWASP Top 10 for LLM Applications (2025) and the OWASP Machine Learning Security Top 10. Expand any flagged control for the exact findings — compromise reduces the score; expected/risk-surface do not, except a known CVE, which carries a small bounded penalty (high/critical → Review).

OWASP Top 10 for LLM Applications
⚠LLM05Improper Output Handlingmedium
Code that pipes model/user output into shell, eval, SQL or paths unsafely.
•Suspicious code patterns — OS command execution · allenai-scispacy-eacccd4/scripts/install_local_packages.py (CWE-78)risk surface
⚠LLM06Excessive Agencymedium
Over-broad tool/permission surface or unrestricted egress.
•External endpoints declared — 1 distinct host(s) · allenai-scispacy-eacccd4/.github/workflows/publish.ymlrisk surface
•External endpoints declared — 14 distinct host(s) · allenai-scispacy-eacccd4/README.mdrisk surface
•External endpoints declared — 7 distinct host(s) · allenai-scispacy-eacccd4/docs/index.mdrisk surface
•External endpoints declared — 6 distinct host(s) · allenai-scispacy-eacccd4/pyproject.tomlrisk surface
•External endpoints declared — 4 distinct host(s) · allenai-scispacy-eacccd4/scispacy/candidate_generation.pyrisk surface
•External endpoints declared — 2 distinct host(s) · allenai-scispacy-eacccd4/scispacy/linking_utils.pyrisk surface
•External endpoints declared — 5 distinct host(s) · allenai-scispacy-eacccd4/tests/test_file_cache.pyrisk surface
⚠LLM10Unbounded Consumptionmedium
Unbounded loops/recursion causing DoS or runaway cost.
Enforced at runtime by the gateway (rate limits + spend caps + size caps); static check flags unbounded loops.
•Potentially unbounded loop — an infinite loop (while True / while(1) / for(;;)) may cause runaway consumption · allenai-scispacy-eacccd4/scispacy/hyponym_detector.py (CWE-835)risk surface
§LLM09MisinformationGovernance
Artifacts designed to produce false/deceptive output.
Detectable only by runtime behavioral evaluation; addressed via responsible-use attestation.
✓LLM01Prompt InjectionPassed
✓LLM02Sensitive Information DisclosurePassed
✓LLM03Supply ChainPassed
✓LLM04Data and Model PoisoningPassed
Backdoors/poisoning in training data or serialized models.
Behavioral poisoning needs model execution; static check covers unsafe serialization + dataset skew only.
✓LLM07System Prompt LeakagePassed
✓LLM08Vector and Embedding WeaknessesPassed
PII or plaintext source leakage in embedding/vector exports.
Embedding inversion/poisoning is largely runtime; static check covers PII in vector exports.
OWASP Machine Learning Security Top 10
⚠ML09Output Integritymedium
Middleware tampering with model outputs in transit.
Gateway enforces TLS + response integrity; static check flags output-rewriting code.
•Suspicious code patterns — OS command execution · allenai-scispacy-eacccd4/scripts/install_local_packages.py (CWE-78)risk surface
§ML01Input Manipulation (Adversarial)Governance
Models vulnerable to adversarial perturbations.
Requires runtime robustness evaluation; addressed via publisher robustness attestation.
§ML03Model InversionGovernance
Training data reconstructable from a model's outputs.
Runtime/evaluation property; addressed via model-card data-provenance + DP attestation.
§ML04Membership InferenceGovernance
Determining whether a record was in the training set.
Runtime/evaluation property; addressed via overfitting disclosure + DP attestation.
§ML08Model SkewingGovernance
Models trained on skewed data producing biased output.
Requires fairness evaluation; addressed via model-card bias/limitations disclosure.
✓ML02Data PoisoningPassed
Poisoned training datasets with triggers or anomalous distributions.
Static check covers trigger phrasing, PII and label skew; full poisoning detection is runtime.
✓ML05Model TheftPassed
Unlicensed re-distribution / license-incompatible derivatives.
Static check verifies license declaration; extraction throttling is runtime.
✓ML06AI Supply ChainPassed
✓ML07Transfer Learning AttackPassed
Backdoored base models / LoRA adapters propagating to derivatives.
Backdoor detection needs behavioral probing; static check covers unsafe serialization + provenance.
✓ML10Model Poisoning (Weights)Passed
Tampered model weight files; integrity must be verifiable.
Static check enforces safe formats + records a content hash for downstream verification.
Other findings (9) · hygiene / uncategorized
•Unrecognized file type — '.flake8' is not on the allowlist · allenai-scispacy-eacccd4/.flake8risk surface
•Unrecognized file type — '.gitignore' is not on the allowlist · allenai-scispacy-eacccd4/.gitignorerisk surface
•Unrecognized file type — '.?' is not on the allowlist · allenai-scispacy-eacccd4/Dockerfilerisk surface
•Unrecognized file type — '.in' is not on the allowlist · allenai-scispacy-eacccd4/MANIFEST.inrisk surface
•Unrecognized file type — '.cfg' is not on the allowlist · allenai-scispacy-eacccd4/configs/base_ner.cfgrisk surface
•Unrecognized file type — '.ini' is not on the allowlist · allenai-scispacy-eacccd4/pytest.inirisk surface
•Unrecognized file type — '.conllu' is not on the allowlist · allenai-scispacy-eacccd4/tests/custom_tests/data_fixtures/test.conllurisk surface
•Unrecognized file type — '.pmids' is not on the allowlist · allenai-scispacy-eacccd4/tests/custom_tests/data_fixtures/test.pmidsrisk surface
•Unrecognized file type — '.rrf' is not on the allowlist · allenai-scispacy-eacccd4/tests/fixtures/umls_META/MRCONSO.RRFrisk surface
✔ verified source · pinned allenai-scispacy-eacccd4
Check against a policy

The same gate an agent runs before installing (POST /api/v1/trust/scispacy-biomedical-nlp/check). Click a policy:

Consume scispaCy — Biomedical & Scientific NLP Models programmatically. Authenticate with an API key or session — see Authorize an agent.

# Agents: CHECK BEFORE YOU INSTALL (no auth) — score, grade, level, capability manifest
curl https://ai-supply.store/api/v1/trust/scispacy-biomedical-nlp

# Gate against your org policy (returns { pass, violations })
curl -X POST https://ai-supply.store/api/v1/trust/scispacy-biomedical-nlp/check \
  -H "Content-Type: application/json" \
  -d '{"minGrade":"B","denyPermissions":["shell"],"denyUnknownEgress":true}'

# CLI
npx ai-supply add scispacy-biomedical-nlp

# REST (install → download)
curl -X POST https://ai-supply.store/api/v1/listings/scispacy-biomedical-nlp/install \
  -H "Authorization: Bearer $AIM_KEY"

# MCP tool
install_listing({ "slug": "scispacy-biomedical-nlp" })
OpenAPI spec →
vlatest
✓ Security: Safe · 1001mo ago

Curated mirror — latest upstream source. See the repository for tagged releases.

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